Study-unit HERBAL PRODUCTS TOSSICOLOGY

Course name Pharmacy
Study-unit Code A000578
Location PERUGIA
Curriculum Comune a tutti i curricula
Lecturer Claudia Zadra
Lecturers
  • Claudia Zadra
Hours
  • 28 ore - Claudia Zadra
CFU 4
Course Regulation Coorte 2018
Supplied 2021/22
Supplied other course regulation
Learning activities Affine/integrativa
Area Attività formative affini o integrative
Sector AGR/13
Type of study-unit Opzionale (Optional)
Type of learning activities Attività formativa monodisciplinare
Language of instruction Italian
Contents Biotransformation of the active ingredients in the complementary medicines and their possible toxic effects.
Occurrence of residues and contaminants in medicinal herbs: source, class of contaminants (heavy metals, pesticides, mycotoxins..) and regulatory limits. Adverse effects of these xenobiotic for the human health.
Reference texts Casarett & Doull’s Toxicology -The basic science of poisons

Melis - Additivi e tossici negli alimenti
Educational objectives One of the goals of the course is to provide information about the biotransformation reactions of the active ingredients with particular attention for the possible toxic effects of some metabolites.
Another topic is to focus critical aspects in terms of the presence of contaminants in botanicals, with respect to their origin, presence in the environment or during the manufacturing process.
Prerequisites The student is requested to know Chemistry, Organic Chemistry and Botany
Teaching methods frontal lectures
Learning verification modality oral examination
Extended program General principles of environmental and food contaminations; risk analysis; risk assessment;
Biotransformation of xenobiotics.
Natural toxicants (Terpenes, Phenylpropanoids, coumarins, nitrates, nitrosamines, cyanogenic compounds, alkaloids).
MICROPOLLUTANTS (heavy metals, dioxins and dioxins compounds like, PAH)
PESTICIDES (environmental fate, Herbicides, Insecticides, Fungicides ,
Pesticides in botanicals
MRLs, )