Study-unit ADVANCED PHARMACEUTICAL TECHNOLOGY AND MEDICAL DEVICES
| Course name | Pharmacy |
|---|---|
| Study-unit Code | A000532 |
| Location | PERUGIA |
| Curriculum | Comune a tutti i curricula |
| Lecturer | Valeria Ambrogi |
| Lecturers |
|
| Hours |
|
| CFU | 6 |
| Course Regulation | Coorte 2020 |
| Supplied | 2024/25 |
| Supplied other course regulation | |
| Learning activities | Caratterizzante |
| Area | Discipline chimiche, farmaceutiche e tecnologiche |
| Sector | CHIM/09 |
| Type of study-unit | Obbligatorio (Required) |
| Type of learning activities | Attività formativa monodisciplinare |
| Language of instruction | Italian |
| Contents | Biopharmaceutics and biopharmaceutic classification system, bioavailability. Modified release drug delivery systems. Legislation and classification od medical devices |
| Reference texts | P. Colombo et al., Principi di Tecnologie Farmaceutiche, Casa Editrice Ambrosiana, 2015; Material given by the teacher |
| Educational objectives | The aim of the course is giving the necessary expertise in the field of modern technology. The student will be able to apply the knowledge of the technological pharmaceutics to the relationships between technological and pharmacokinetic properties of the modern drug dosage forms. The student will frame medical devices from a regulatory point of view |
| Prerequisites | The student has to possess the basic notions of the conventional pharmaceutical dosage forms and to the drug legislation |
| Teaching methods | Face -to -face lessons |
| Other information | Lessons take place at the Department of Pharmaceutical Sciences according to the calendar published on the appropriate website. For information on support services for students with disabilities and / or DSA visit the page http://www.unipg.it/disabilita-e-dsa |
| Learning verification modality | The exam consists of an oral test which consists of a discussion-interview on the topics discussed during the course. The exam is passed if the student gets at least 18/30 .The test lasts about 30 minutes , but it depends on the performance of the test itself. The oral test aims at verifying the level of knowledge and understanding, as well as synthesis, achieved by the student. Moreover this oral test will verify if the student is able to communicate, his property of language and exposition as concerns the studied topics. |
| Extended program | Biopharmaceutics and Biopharmaceutic classification system. Modified release dosage forms: definition and relative bioavailability profile. Drug solubility and technological approaches for improving apparent solubility and dissolution rate: polymorphs, amorphous and hydrate form, nanocrystals. Use of cosolvent and complexes. Solid dispersions: classification, preparation, advantages and applications. Cyclodextrins: definition, classification, derivatives, complexes of drug and cyclodextrins, applications. Lipidic oral formulations: definition, advantages and applications. Modified release systems, matrix and reservoir formulations, kinetics of release. Microparticles: definition, general method of preparation, classification, advantages and application. Gastroretentive systems: definition, advantages, application. Mucoadhesive systems: definition, advantages, classification, applications. Orodispersible tablets: definition, advantages and classification. Formulations for cronotherapy. Osmotic systems: definition, classification, characteristics and advantages of the different kinds of osmotic pomps (elemental, puch pull, puch stick), kinetics of release. Colonic drug delivery: advantages and tecnological strategies, applications. Transdermal delivery systems: definition, characteristics, classification, applications. Ophtalmic systems for modified release. Modified release through vaginal route. Liposomes: definition, compositions, classifications, applications. Drug targeting: active and passive drugg targeting: advantages, applications. Nasal and polmonary drug delivery systems. Legislation of medical devices and classification.Examples of medical devices: for wounds, for oral care, for ostomies |