Study-unit FOOD-DRUG BIOCHEMICAL INTERACTIONS
| Course name | Pharmacy |
|---|---|
| Study-unit Code | A003578 |
| Curriculum | Comune a tutti i curricula |
| Lecturer | Michela Codini |
| Lecturers |
|
| Hours |
|
| CFU | 4 |
| Course Regulation | Coorte 2022 |
| Supplied | 2025/26 |
| Supplied other course regulation | |
| Learning activities | Affine/integrativa |
| Area | Attività formative affini o integrative |
| Sector | BIO/10 |
| Type of study-unit | Opzionale (Optional) |
| Type of learning activities | Attività formativa monodisciplinare |
| Language of instruction | Italian |
| Contents | The course aims to investigate drug-food interactions from both a pharmacological and nutritional perspective. |
| Reference texts | Lecture notes and slides provided by the lecturer |
| Educational objectives | Enable the pharmacist to gain knowledge about possible interactions between drug molecules, food and drink in order to advise on the best way to administer a drug. |
| Prerequisites | Knowledge of biochemistry, physiology and pharmacology. |
| Teaching methods | Lectures |
| Other information | Recommended attendance |
| Learning verification modality | Student assessment is done by oral examination. The oral test consists of a discussion of about 30 minutes aimed at ascertain the knowledge level and the understanding capability acquired by the student on theoretical contents as indicated on the program. The oral exam will also test the student communication skills and his autonomy in the organization and exposure of the theoretical topics. |
| Extended program | Introduction to the course. Nutrient-drug and drug-nutrient interactions. Possible mechanisms of interaction: pharmacokinetic interactions and/or pharmacodynamic interactions. Recalls of pharmacokinetics. Factors influencing drug absorption: drug-specific and patient-specific. Influence of food on drug dissolution. Uptake and efflux transporters. Effect of meals on gastrointestinal drug metabolism. Effect of dietary components (nutrients) on drug metabolism. Effects of alcohol, coffee, spices, juices. Nutritional status and drugs: drugs associated with weight gain or weight loss. Drugs that alter gastrointestinal function. Metabolic effects of drugs: alterations in glucose, lipid and protein metabolism. Possible effect of drugs on mineral and vitamin metabolism. Nutritional status and drugs: overweight-obesity and malnutrition |