Study-unit GENERAL PHARMACOLOGY
| Course name | Biotechnology |
|---|---|
| Study-unit Code | 55058306 |
| Curriculum | Comune a tutti i curricula |
| Lecturer | Maria Teresa Pallotta |
| Lecturers |
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| Hours |
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| CFU | 6 |
| Course Regulation | Coorte 2022 |
| Supplied | 2024/25 |
| Supplied other course regulation | |
| Learning activities | Affine/integrativa |
| Area | Attività formative affini o integrative |
| Sector | BIO/14 |
| Type of study-unit | Opzionale (Optional) |
| Type of learning activities | Attività formativa monodisciplinare |
| Language of instruction | Italian |
| Contents | Pharmacokinetics: the dynamic of drug absortion, distribution, metabolism and elimination. Routes of administration Pharmacodynamics - Molecular drug targets - Families of receptors and signaling pathways - Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-protein-coupled receptor, receptor protein kinases, intracellular receptors). - Transcription factors. - Agonist and antagonist ligands - Regulation of receptors - Pharmacogenomics and pharmacogenetics - Pharmacology of biotechnologic drugs |
| Reference texts | Paoletti, Nicosia, Clementi, Fumagalli "Farmacologia generale e molecolare" UTET and H.P. Rang & M.M. Dale FARMACOLOGIA EDRA Ed. – SETTIMA EDIZIONE |
| Educational objectives | Biotechnologic competence - Knowledge and comprehension of the production, analysis and control of drugs obtained by means of biotechnologic processes; general principles of pharmacology in relationship to the project of drugs and in general of bioactive molecules obtained by means of biotechnologic processes; structura and biologic properties of animal and plant cells and tissues. |
| Prerequisites | Having passed the exams of Biochemistry and Principles of Anatomy and General Physiology |
| Teaching methods | Face-to-face theoretical lessons |
| Other information | Students with disabilities and/or DSA are invited to visit the page dedicated to the tools and measures envisaged and to agree in advance what is necessary with the teacher (https://www.unipg.it/disabilita-e -dsa) |
| Learning verification modality | Oral exam, aimed at determining knowledge of both pharmacokinetics and pharmacodynamics, which are the fundamental elements for the correct use and design of a drug |
| Extended program | Introduction to pharmacology. Concept of drug and medication. Chemical and physical properties of drugs. Pharmacokinetics: the dynamic of drug absortion, distribution, metabolism and elimination. Routes of administration Pharmacodynamics - Molecular drug targets - Families of receptors and signaling pathways - Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-protein-coupled receptor, receptor protein kinases, intracellular receptors). - Transcription factors. - Agonist and antagonist ligands - Regulation of receptors - Pharmacogenomics and pharmacogenetics - Pharmacology of biotechnologic drugs |