Study-unit NMR TECHNIQUES IN PHYSIOLOGY AND MEDICINE
Course name | Physics |
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Study-unit Code | A002576 |
Location | PERUGIA |
Curriculum | Fisica medica |
Lecturer | Roberto Tarducci |
Lecturers |
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Hours |
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CFU | 6 |
Course Regulation | Coorte 2022 |
Supplied | 2022/23 |
Supplied other course regulation | |
Learning activities | Affine/integrativa |
Area | Attività formative affini o integrative |
Sector | FIS/07 |
Type of study-unit | Opzionale (Optional) |
Type of learning activities | Attività formativa monodisciplinare |
Language of instruction | Italian |
Contents | 1. Classical description of NMR; 2. Density matrix description of NMR; 3. Pulsed NMR 4. Applications |
Reference texts | MH Levitt - Spin Dynamics Basics of Nuclear Magnetic Resonance (2nd edition) Wiley (2008); C Costantinides "Magnetic Resonace Imaging - the basic" CRC Press (2014) |
Educational objectives | To understand theoretical description of NMR phenomenon and its medical applications. The application will concern: 1. NMR spectroscopy in vivo; 2. study of the cerebral activation of the motor areas; 3. measurement of the brain water diffusion tensor. |
Prerequisites | Statistical physics, quantum mechanics, classical electrodynamics |
Teaching methods | interactive lesson |
Learning verification modality | required to pass an oral examination |
Extended program | 1) Physical foundations of magnetic resonance imaging a. Treatment of the physical foundations of magnetic resonance imaging; b. Structure of an NMR scanner for clinical use; (10 lessons) 2) Biophysical aspects of nuclear spin relaxation a. Relaxation mechanisms; b. Contrasts in T1, T2 and proton density; c. Paramagnetic contrast media. (2 lessons) 3) Reconstruction of magnetic resonance images a. Magnetic field gradients and slice selection; b. Phase and frequency encoding; c. Trajectories in space k; d. Spin echo sequence; e. Images based on the gradient echo; f. Bloch equation simulation. (7 lessons) |