Study-unit BIOCOMPATIBLE MATERIALS
| Course name | Molecular and industrial biotechnology |
|---|---|
| Study-unit Code | GP004121 |
| Curriculum | Comune a tutti i curricula |
| Lecturer | Assunta Marrocchi |
| Lecturers |
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| Hours |
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| CFU | 6 |
| Course Regulation | Coorte 2022 |
| Supplied | 2022/23 |
| Learning activities | Caratterizzante |
| Area | Discipline chimiche |
| Sector | CHIM/06 |
| Type of study-unit | Obbligatorio (Required) |
| Type of learning activities | Attività formativa monodisciplinare |
| Language of instruction | Italian |
| Contents | Biomaterials & Biocompatibility. Polymeric, ceramic and metallic biomaterials. Composites. Analytical methods for biomaterials surface characterization. Surface modification of biomaterials. Established biomaterials-based technologies. Bioelectronics. |
| Reference texts | -Power point slides and scientific articles will be provided SUGGESTED TEXTBOOKS: -L. Stanciu, S. Diaz-Amaya ‘’Introductory Biomaterials. An overview of key concepts’’. 1st edition. Academic Press, 2021. -C. Di Bello, A. Bagno ‘’Biomateriali. Dalla scienza dei materiali alle applicazioni cliniche’’. 2° edizione. Patròn Editore, 2016 -A. Marrocchi Ed. “Sustainable strategies in organic electronics” (I Ed., 2022) – Woodhead Publishing, Elsevier [ISBN 978-0-12-823147-0] |
| Educational objectives | The main objective of the course is to provide to students the basic knowledge about chemical-physical aspects and the development of biocompatible materials, to rationally elaborate selection criteria for their design/use in the fields of application discussed during lectures. The main knowledge acquired will be: -knowledge of (i) definition of biomaterial and biocompatibility (ii) definition of solid state, main crystalline networks and their principal defects; -basic knowledge of the electrical, optical, thermal properties of solid materials; -knowledge of the fundamental concepts of stress, strain, rigidity, resistance, toughness of biocompatible materials; -knowledge of the main classes of biocompatible materials: Polymers (classification on the basis of their chemical-physical and mechanical properties; polymerization reactions; main classes of interest); Ceramics and glass-ceramics (traditional and advanced materials); Metals and alloys; Composites; -basic knowledge of their main production techniques and influence of these latter on the operational material behavior; -knowledge of the biomaterials corrosion phenomena in a biological environment and relative issues; -knowledge of the main instrumental techniques for the study of biomaterials surface, to evaluate their biocompatibility; -knowledge of the main techniques for biomaterials surface modification, to adjust biocompatibility; -basic knowledge of selected biomaterials-based sensors for application in medical and biological field. The main abilities will be: -ability in elaborating criteria of choice for the design and synthesis of 3D structures to be employed in the field discussed during lectures. -ability in identifying the most suitable instrumental techniques for the characterization of biomaterials surfaces, in view of evaluating their biocompatibility -ability in identifying the most suitable techniques for biomaterials surface modification, in view of improving their biocompatibility. |
| Prerequisites | none |
| Teaching methods | Face-to-face lectures on all the topics of the course. During the course there might be the possibility to organize seminars in which external experts will report about their practical experience on the use of advanced instrumental techniques for the study of biomaterials surfaces. |
| Learning verification modality | Oral exam. Time of duration: about 30 min. The exam will consist of open questions aiming at assessing the level of knowledge/expertise achieved by the student on the course topics. Further, through the exam will be evaluated the student's communication skills and ability of logically organize the discussion. |
| Extended program | Biomaterials & Biocompatibility. Reference to the main types of chemical bonding. Solid state. Solid materials properties (mechanical, thermal, optical). Polymeric, ceramic/glass-ceramic and metallic biomaterials: classification, synthesis, production tecniques, main classes of interest. (nano)Composites. Established biomaterials-based technologies. Main analytical methods for biomaterials surface characterization. Surface modification of biomaterials. Bioelectronics. Other emerging and future biomaterials-based technologies. Reference to the existing normative. |