| Course name |
Medical, veterinary and forensic biotechnological sciences |
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| Study-unit Code |
A001764 |
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| Curriculum |
Comune a tutti i curricula |
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| Lecturer |
Paolo Gresele |
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| Lecturers |
- Paolo Gresele
- Loredana Bury (Codocenza)
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| Hours |
- 33 ore - Paolo Gresele
- 19 ore (Codocenza) - Loredana Bury
|
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| CFU |
6 |
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| Course Regulation |
Coorte 2022 |
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| Supplied |
2022/23 |
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| Learning activities |
Caratterizzante |
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| Area |
Discipline di base applicate alle biotecnologie |
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| Sector |
MED/09 |
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| Type of study-unit |
Obbligatorio (Required) |
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| Type of learning activities |
Attività formativa monodisciplinare |
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| Language of instruction |
English |
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| Contents |
Coagulation, Approach to the patient with hemorrhagic diathesis, Diagnostic tests, Flow cytometry applied to the study of hemostasis, Megakaryocytes and platelet formation, Cellular models for the study of inherited platelet disorders, Laboratory monitoring of antithrombotic drugs, Micro-RNA in hemostasis and thrombosis, DVT and thrombophilia, PCR, Real Time PCR and sequencing applied to hematoma and thrombosis pathologies, Interaction between dyslipidemia and hemostasis and thrombosis, autoimmune thrombocytopenias and platelet function disorders, Congenital hemorrhagic diseases and acquired coagulopathies, Animals models for the study of hemostasis, thrombosis and atherosclerosis, Methods for the study of endothelial cells. Cellular models for the study of inherited platelet disorders. |
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| Reference texts |
The teacher will prepare the didactic materials on the basis of the scientific literature available on the specific topics. Accordingly, participation to the teacher's lessons is essential. On specific topics, references to specific articles or textbooks will be provided. |
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| Educational objectives |
The course aims to provide students with the basic knowledge on the diagnostic and therapeutic techniques and the most updated biotechnological methods in the field of hemostasis and thrombosis. |
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| Prerequisites |
General biology, animal and vegetal models for biotecnology, molecular biology, general principles of anatomy and physiology, pharmacology |
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| Teaching methods |
Didactic activity will be mainly focused on face-to-face lessons using Power Point slides, practical lessons with laboratory techniques will be made at the Hemostasis and Thrombosis Centre. |
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| Other information |
The attendance to at least 80% of the lessons is required in order to allow a good understanding of the discussed to pics in the absence of a single reference textbook. Materials presented topics during classes will be made available after the lessons. |
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| Learning verification modality |
Multiple choice and free text, written assessment |
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| Extended program |
The hemostatic process: pathophysiology and clinical aspects.Approach to the patient with suspected hemorrhagic disorders. Main diseases in the field of hemostasis and thrombosis (genetic and acquired hemorrhagic disorders including hemophilia A and B, other coagulation factor deficiencies, von Willebrand disease, disseminated intravascular coagulation);Megacaryocytes and thrombocytopoiesis. Cellular models for the study of inherited platelet disorders. Flow cytometry applied to the study of hemostasis. Diagnostic tests for platelet disorders. Venous thromboembolism and the study of congenital and acquired thrombophilia. MicroRNA in hemostasis and thrombosis. Molecular biology techniques applied to hemostasis and thrombosis. Animal models in biomedical research in the field of hemostasis, thrombosis and atheroclerosis. Immunologic thrombocytopenias. Laboratory monitoring of antithrombotic drugs. Methods for the suty of endothelial cells- Interaction between lipids and hemostatic system |
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