Study-unit GENETICS AND EPIGENETICS
| Course name | Medical, veterinary and forensic biotechnological sciences |
|---|---|
| Study-unit Code | A001761 |
| Curriculum | Comune a tutti i curricula |
| Lecturer | Enrico Tiacci |
| Lecturers |
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| Hours |
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| CFU | 6 |
| Course Regulation | Coorte 2022 |
| Supplied | 2022/23 |
| Supplied other course regulation | |
| Learning activities | Caratterizzante |
| Area | Discipline biotecnologiche comuni |
| Sector | BIO/18 |
| Type of study-unit | Obbligatorio (Required) |
| Type of learning activities | Attività formativa monodisciplinare |
| Language of instruction | English |
| Contents | Principles of genetics and epigenetics in general, and in blood diseases in particular |
| Reference texts | Slides presented and provided by the teacher, and made available in UNISTUDIUM |
| Educational objectives | The main objective of this course is to provide students with: - the theoretical basis to acquire the knowledge of the genetic and epigenetic mechanisms underlying human diseases, in particular those of the blood - the practical basis to leverage the knowledge of such mecahnisms for diagnostic and therapeutic purposes |
| Prerequisites | A solid knowledge of the following subjects is required: Genetics Immunology Molecular biology General biology with elements of cytology and histology Principles of anatomy and general physiology Biochemistry Farmacology Basic bioinformatics and systems biology |
| Teaching methods | Theoretical and practical lessons To give continuity to educational activities, during the pandemic caused by COVID-19, we used the UNISTUDIUM platform to carry out online lessons and exams |
| Other information | None |
| Learning verification modality | Single, multiple-choice written exam (31 questions; 2-hour duration; no penalization for wrong answers), which may be followed by an oral exam at the discretion of the student if obtaining a vote equal to or greater than 28/30 at the written exam. |
| Extended program | Genetics and Epigenetics: Introduction Hematopoiesis Genetics and epigenetics of myeloid tumors (Epi-)Genetics of hemoglobinopathies and thalassemias Genetics-based diagnostic methods for hemoglobinopathies and thalassemias Genetics and epigenetics of mature lymphoid leukemias and lymphomas Sanger and next-generation sequencing of nucleic acids. Digital PCR Genetic engineering of eukaryotic cells Gene therapy |