Study-unit ADVANCED MOLECULAR BIOLOGY
| Course name | Biology |
|---|---|
| Study-unit Code | GP004083 |
| Curriculum | Biomolecolare |
| Lecturer | Sabata Martino |
| Lecturers |
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| Hours |
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| CFU | 6 |
| Course Regulation | Coorte 2022 |
| Supplied | 2022/23 |
| Supplied other course regulation | |
| Learning activities | Caratterizzante |
| Area | Discipline del settore nutrizionistico e delle altre applicazioni |
| Sector | BIO/13 |
| Type of study-unit | Obbligatorio (Required) |
| Type of learning activities | Attività formativa monodisciplinare |
| Language of instruction | Italian |
| Contents | Biological relevance of the basic biological molecular mechanisms Advancing applications in the biomedical, nutrition and environment fields. Molecular mechanisms of stem cell biology. Regulation of gene expression Apoptosis Aging mechanisms |
| Reference texts | Educational slides provided by the teacher LEWIN Benjamin IL GENE X Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monthy Krieger, Matthew P. Scott, Antony Bretscher, Hidde Ploegh, Paul Matsudaira Molecular cell biology James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick ed, Molecular biology of the gene . Helen Kreuzer, Adrianne Massey Molecular Biology and Biotechnology |
| Educational objectives | Mechanisms of regulation of gene expression. Relevance of molecular mechanisms of animal and plant biology. Molecular mechanisms of stem cell biolog |
| Prerequisites | Molecular Biology, Biochemistry ChemistryùCellular Biology |
| Teaching methods | Lectures will be made by using slides and movies. Some lessons could be dedicated to innovative issues also proposed by students, with the involvement of students themselves. Practical lessons (1 CFU) will be held in the laboratory and will focus on basic methodologies such as transfection of nucleic acids on host cells and analysis of recombinant proteins by immunofluorence. |
| Other information | It is planned a tutorial activity during the course and for students who request help for the preparation of the exam. The dates of receipt students are available in the professor's website. |
| Learning verification modality | Oral exam |
| Extended program | Regulation of gene expression: mechanisms of gene activation and repression. MicroRNA; Long non-coding-RNA; CE-RNA. Mechanism of gene repragramming . Molecular mechanism of cell cycle. Apoptosis. Molecular mechanism of Aging . Stem cells and regulatory mechanism. Stem cell: therapeutic applications. Induced pluripoten stem cells. Gene therapy. Interactions between macromolecules: mechanisms and biological significance. Molecular Basicmechanisms as substrate for the development of biotechnologies. |