Study-unit PRINCIPLES OF INDUSTRIAL MICROBIOLOGY
| Course name | Industrial pharmacy |
|---|---|
| Study-unit Code | A000579 |
| Curriculum | Comune a tutti i curricula |
| Lecturer | Laura Corte |
| Lecturers |
|
| Hours |
|
| CFU | 4 |
| Course Regulation | Coorte 2023 |
| Supplied | 2023/24 |
| Supplied other course regulation | |
| Learning activities | Affine/integrativa |
| Area | Attività formative affini o integrative |
| Sector | AGR/16 |
| Type of study-unit | Opzionale (Optional) |
| Type of learning activities | Attività formativa monodisciplinare |
| Language of instruction | Italian |
| Contents | Microorganisms of industrial interest - Products of microbial metabolism - Mutants for industrial use and mutagenesis techniques - Fermentation biotechnology: commercial and metabolic classifications; types of management; immobilization of microbial cells - Kinetic aspects of microbiological processes - Isolation of fermentation products (downstream). Fermentation plants - Microbial metabolites of pharmaceutical interest |
| Reference texts | M. MANZONI. Microbiologia Industriale, Casa Editrice Ambrosiana Brock. Biologia dei microrganismi. Microbiologia generale, ambientale e industriale. Ediz. Mylab. |
| Educational objectives | Knowledge of the basic elements of Industrial Microbiology completes and enhances the training of a graduate in Chemistry and Pharmaceutical Technologies. The course aims to illustrate to the student the processes and principles underlying the microbial production of metabolites of industrial interest and their use in pharmaceutical biotechnology. |
| Prerequisites | Basic knowledge of microbiology, biochemistry and mathematics. |
| Teaching methods | Lectures, written and oral tests. |
| Other information | Please visit the department website for additional information. For information on support services for students with disabilities and/or DSA visit the page http://www.unipg.it/disabilita-e-dsa |
| Learning verification modality | Written and oral exams. |
| Extended program | Main microorganisms of industrial interest. Products of microbial metabolism: primary products and secondary products; strategies for the accumulation of microbial metabolites. Sources of isolation, primary and secondary screening, mutagenesis, selection. Substrates for industrial fermentations; Criteria for the classification and differentiation of industrial fermentations; kinetic aspects of microbiological processes. Type I, II and III kinetics; culture methods: solid state fermentation, surface culture, submerged culture; batch, fed-batch, continuous fermentation technology. Industrial fermenters; Sterilization of fermenters and substrates. Isolation of fermentation products (downstream) and determination of the biological activity of metabolites of microbial origin. Immobilization procedures for microbial cells: Fermentors for immobilized microbial cells. Microbial products of pharmaceutical interest. |
| Obiettivi Agenda 2030 per lo sviluppo sostenibile | 7. Clean and affordable energy; 9. Industry, innovation and infrastructure; 12. Responsible consumption and production; 13. Act for the climate |