| Course name |
Biotechnology |
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| Study-unit Code |
55058306 |
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| Curriculum |
Comune a tutti i curricula |
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| Lecturer |
Maria Teresa Pallotta |
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| Lecturers |
|
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| Hours |
- 42 ore - Maria Teresa Pallotta
|
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| CFU |
6 |
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| Course Regulation |
Coorte 2023 |
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| Supplied |
2025/26 |
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| Supplied other course regulation |
|
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| Learning activities |
Affine/integrativa |
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| Area |
Attività formative affini o integrative |
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| Sector |
BIO/14 |
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| Type of study-unit |
Opzionale (Optional) |
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| Type of learning activities |
Attività formativa monodisciplinare |
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| Language of instruction |
Italian |
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| Contents |
Pharmacokinetics: the dynamic of drug absortion, distribution, metabolism and elimination. Routes of administration Pharmacodynamics - Molecular drug targets - Families of receptors and signaling pathways - Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-protein-coupled receptor, receptor protein kinases, intracellular receptors). - Transcription factors. - Agonist and antagonist ligands - Regulation of receptors - Pharmacogenomics and pharmacogenetics - Pharmacology of biotechnologic drugs |
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| Reference texts |
Paoletti, Nicosia, Clementi, Fumagalli "Farmacologia generale e molecolare" UTET and H.P. Rang & M.M. Dale FARMACOLOGIA EDRA Ed. – SETTIMA EDIZIONE |
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| Educational objectives |
Biotechnologic competence - Knowledge and comprehension of the production, analysis and control of drugs obtained by means of biotechnologic processes; general principles of pharmacology in relationship to the project of drugs and in general of bioactive molecules obtained by means of biotechnologic processes; structura and biologic properties of animal and plant cells and tissues. |
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| Prerequisites |
Having passed the exams of Biochemistry and Principles of Anatomy and General Physiology |
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| Teaching methods |
Face-to-face theoretical lessons |
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| Other information |
Students with disabilities and/or DSA are invited to visit the page dedicated to the tools and measures envisaged and to agree in advance what is necessary with the teacher (https://www.unipg.it/disabilita-e -dsa) |
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| Learning verification modality |
Oral exam, aimed at determining knowledge of both pharmacokinetics and pharmacodynamics, which are the fundamental elements for the correct use and design of a drug |
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| Extended program |
Introduction to pharmacology. Concept of drug and medication. Chemical and physical properties of drugs. Pharmacokinetics: the dynamic of drug absortion, distribution, metabolism and elimination. Routes of administration Pharmacodynamics - Molecular drug targets - Families of receptors and signaling pathways - Quantitation of drug-receptor interaction and effects, radioligand binding method, molecular characterization (ion channels, G-protein-coupled receptor, receptor protein kinases, intracellular receptors). - Transcription factors. - Agonist and antagonist ligands - Regulation of receptors - Pharmacogenomics and pharmacogenetics - Pharmacology of biotechnologic drugs |
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| Obiettivi Agenda 2030 per lo sviluppo sostenibile |
Health and wellbeing |
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