Study-unit NMR TECHNIQUES IN PHYSIOLOGY AND MEDICINE
| Course name | Physics |
|---|---|
| Study-unit Code | A002576 |
| Location | PERUGIA |
| Curriculum | Fisica medica |
| Lecturer | Roberto Tarducci |
| Lecturers |
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| Hours |
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| CFU | 6 |
| Course Regulation | Coorte 2023 |
| Supplied | 2024/25 |
| Supplied other course regulation | |
| Learning activities | Affine/integrativa |
| Area | Attività formative affini o integrative |
| Sector | FIS/07 |
| Type of study-unit | Opzionale (Optional) |
| Type of learning activities | Attività formativa monodisciplinare |
| Language of instruction | Italian |
| Contents | 1. Classical description of NMR; 2. Density matrix description of NMR; 3. Pulsed NMR 4. Applications |
| Reference texts | MH Levitt - Spin Dynamics Basics of Nuclear Magnetic Resonance (2nd edition) Wiley (2008); C Costantinides "Magnetic Resonace Imaging - the basic" CRC Press (2014) |
| Educational objectives | To understand theoretical description of NMR phenomenon and its medical applications. The application will concern: 1. NMR spectroscopy in vivo; 2. study of the cerebral activation of the motor areas; 3. measurement of the brain water diffusion tensor. |
| Prerequisites | Statistical physics, quantum mechanics, classical electrodynamics |
| Teaching methods | Interactice lesson |
| Learning verification modality | required to pass an oral examination |
| Extended program | 1) Physical foundations of magnetic resonance imaging a. Treatment of the physical foundations of magnetic resonance imaging; b. Structure of an NMR scanner for clinical use; (10 lessons) 2) Biophysical aspects of nuclear spin relaxation a. Relaxation mechanisms; b. Contrasts in T1, T2 and proton density; c. Paramagnetic contrast media. (2 lessons) 3) Reconstruction of magnetic resonance images a. Magnetic field gradients and slice selection; b. Phase and frequency encoding; c. Trajectories in space k; d. Spin echo sequence; e. Images based on the gradient echo; f. Bloch equation simulation. (7 lessons) |